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Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moietyTICHY, Tomas; ANDREI, Graciela; SNOECK, Robert et al.European journal of medicinal chemistry. 2012, Vol 55, pp 307-314, issn 0223-5234, 8 p.Article

Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4'-phosphonobut-2'-en-1'-yl]purine nucleosidesPRADERE, Ugo; ROY, Vincent; MONTAGU, Aurélien et al.European journal of medicinal chemistry. 2012, Vol 57, pp 126-133, issn 0223-5234, 8 p.Article

An efficient and regioselective synthesis of acyclic C-nucleosides from mesoionic compoundsAVALOS, M; BABIANO, R; BAUTISTA, I et al.Carbohydrate research. 1989, Vol 186, Num 2, pp C7-C8, issn 0008-6215Article

The clinical potential of the acyclic (and cyclic) nucleoside phosphonates. The magic of the phosphonate bondDE CLERCQ, Erik.Biochemical pharmacology. 2011, Vol 82, Num 2, pp 99-109, issn 0006-2952, 11 p.Article

Catalytic effect of tetrabutylammonium fluoride in the preparation of secoribo-nucleosidesHAKIMELAHI, G. H; ALI KHALAFI-NEZHAD.Helvetica chimica acta. 1989, Vol 72, Num 7, pp 1495-1500, issn 0018-019X, 6 p.Article

Synthesis of acyclic analogs of azido-thymidine, amino-thymidine, and related nucleosidesTRINH, M.-C; FLORENT, J.-C; GRIERSON, D. S et al.Tetrahedron letters. 1991, Vol 32, Num 11, pp 1447-1448, issn 0040-4039, 2 p.Article

Involvement of adenosine A1 receptors in upregulation of nitric oxide by acyclic nucleotide analoguesZIDEK, Zdenek; KMONICKOVA, Eva; HOLY, Antonin et al.European journal of pharmacology. 2004, Vol 501, Num 1-3, pp 79-86, issn 0014-2999, 8 p.Article

Differential effects of acyclic nucleoside phosphonates on nitric oxide and cytokines in rat hepatocytes and macrophagesKOSTECKA, Petra; HOLY, Antonín; FARGHALI, Hassan et al.International immunopharmacology (Print). 2012, Vol 12, Num 2, issn 1567-5769, 342-347, 349 [7 p.]Article

Analogues of acyclic nucleosides derived from tris-(hydroxymethyl)phosphine oxide or bis-(hydroxymethyl)phosphinic acid coupled to DNA nucleobasesNAWROT, Barbara; MICHALAK, Olga; DE CLERCQ, Erik et al.Antiviral chemistry & chemotherapy. 2004, Vol 15, Num 6, pp 319-328, issn 0956-3202, 10 p.Article

Enhanced Topical and Transdermal Delivery of Antineoplastic and Antiviral Acyclic Nucleoside Phosphonate cPr-PMEDAPVAVROVA, Kateřina; KOVARIKOVA, Petra; SKOLOVA, Barbora et al.Pharmaceutical research. 2011, Vol 28, Num 12, pp 3105-3115, issn 0724-8741, 11 p.Article

Optimisation of aciclovir poly(D, L-lactide-co-glycolide) microspheres for intravitreal administration using a factorial design studyMARTINEZ-SANCHO, C; HERRERO-VANRELL, R; NEGRO, S et al.International journal of pharmaceutics. 2004, Vol 273, Num 1-2, pp 45-56, issn 0378-5173, 12 p.Article

Pharmacokinetics of new antiherpetic agentsROLAN, P.Clinical pharmacokinetics. 1995, Vol 29, Num 5, pp 333-340, issn 0312-5963Article

9-(difluorophosphonoalkyl)guanines as a new class of multisubstrate analogue inhibitors of purine nucleoside phosphorylaseHALAZY, S; EHRHARD, A; DANZIN, C et al.Journal of the American Chemical Society. 1991, Vol 113, Num 1, pp 315-317, issn 0002-7863, 3 p.Article

Synthesis and immunobiological activity of base substituted 2-amino-3-(purin-9-yl)propanoic acid derivativesDOLAKOVA, Petra; HOLY, Antonin; ZIDEK, Zdenek et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 7, pp 2349-2354, issn 0968-0896, 6 p.Article

Point mutations in human guanylate kinase account for acquired resistance to anticancer nucleotide analogue PMEGMERTLIKOVA-KAISEROVA, Helena; RUMLOVA, Michaela; TLOUST'OVA, Eva et al.Biochemical pharmacology. 2011, Vol 82, Num 2, pp 131-138, issn 0006-2952, 8 p.Article

Immunobiological activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N6-substituted adenines, and 2,6-diaminopurinesZIDEK, Zdenek; POTMESIL, Petr; KMONIEKOVA, Eva et al.European journal of pharmacology. 2003, Vol 475, Num 1-3, pp 149-159, issn 0014-2999, 11 p.Article

Role of Caspases and CD95/Fas in the Apoptotic Effects of a Nucleotide Analog PMEG in CCRF-CEM CellsMERTLIKOVA-KAISEROVA, Helena; VOTRUBA, Ivan; MATOUSOVA, Marika et al.Anticancer research. 2010, Vol 30, Num 7, pp 2791-2798, issn 0250-7005, 8 p.Article

Involvement of MAP Kinases in the Cytotoxicity of Acyclic Nucleoside PhosphonatesMERTLIKOVA-KAISEROVA, Helena; NEJEDLA, Michaela; HOLY, Antonin et al.Anticancer research. 2012, Vol 32, Num 2, pp 497-501, issn 0250-7005, 5 p.Article

Stability of ganciclovir in blood samplesBOULIEU, R; BLEYZAC, N.Journal of pharmaceutical and biomedical analysis. 1994, Vol 12, Num 9, pp 1205-1207, issn 0731-7085Article

Purine acyclic nucleosides. 6-dimethylamino-9-[(2-phenylalanylamido-1-substituted-ethoxy)methyl]purines as candidate antiviralsKELLEY, J. L; SELWAY, J. W. T; SCHAEFFER, H. J et al.Journal of pharmaceutical sciences. 1985, Vol 74, Num 12, pp 1302-1304, issn 0022-3549Article

Varicelle et aciclovirGUILLET, G.Médecine & enfance. 2005, Vol 25, Num 4, pp 202-203, issn 0291-0233, 2 p.Article

Aciclovir = AcyclovirLa Revue Prescrire. 1995, Vol 15, Num 156, issn 0247-7750, p. 737Article

Leading articleEASTERBROOK, P; WOOD, M. J.Journal of antimicrobial chemotherapy (Print). 1994, Vol 34, Num 3, pp 307-311, issn 0305-7453Article

Synthesis of novel 3',4'-seco analogues of didehydro dideoxy nucleosides as potential antiviral agentsJOKIC, M; SKARIC, V.Tetrahedron letters. 1994, Vol 35, Num 18, issn 0040-4039, 2815, 2937-2940 [5 p.]Article

Aciclovir et infections dues au virus varicelle-zona = Acyclovir and herpes virus infectionsVILDE, J.-L; LONGUET, P.La Revue du praticien (Paris). 1994, Vol 44, Num 16, pp 2133-2136, issn 0035-2640Article

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